INATE - INvestigators Against ThromboEmbolism
Prevention of Venous thrombosis in Non-surgical patients – A Need for New Recommendations
1. Prevention of Venous-thrombosis in Non-surgical patients - A Need for New Recommendations


Sylvia Haas, MD

  Slide notes:
Venous thromboembolism (VTE) remains a major cause of mortality and morbidity in hospital patients, despite the availability of effective prophylactic agents [1]. Studies demonstrate that the majority of patients who suffer a fatal pulmonary embolism (PE) have not undergone recent surgery [2], but PE is rarely suspected as a cause of death in non-surgical patients [2,3] and prophylaxis is infrequently used [4], despite consensus statement recommendations  [5-7].

1. Anderson FA, et al. A population-based perspective of the hospital incidence and case-fatality rates of deep vein thrombosis and pulmonary embolism. The Worcester DVT study. Arch Intern Med 1991;151:933-8.
2. Sandler DA, Martin JF. Autopsy proven pulmonary embolism in hospital patients: are we detecting enough deep vein thrombosis? J Royal Soc Med 1989;82:203-5.
3. Goldhaber SZ, et al. Risk factors for pulmonary embolism - the Framingham study. JAMA 1983;74:1023-8.
4. Anderson FA, et al. Physician practices in the prevention of venous thromboembolism. Ann Intern Med 1991;115:591-5.
5. Clagett GP, et al. Prevention of venous thromboembolism. Chest 1998;114(5 suppl):531S-60S.
6. Second Thromboembolic Risk Factors (THRIFT II) Consensus Group. Risk of and prophylaxis for venous thromboembolism in hospital patients. Phlebology 1998;13:87-97.
7. Nicolaides AN, et al. Consensus statement. Prevention of venous thromboembolism. Int Angiol 1997;16:3-38.
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